Publications - The Bähr Lab

Most Recent Publications of our Group

Publications 2017

Maier IL, Behme D, Schnieder M, Tsogkas I, Schregel K, Bähr M, Knauth M, Liman J, Psychogios MN.
Early computed tomography-based scores to predict decompressive hemicraniectomy after endovascular therapy in acute ischemic stroke.
PLoS One. 2017 Mar 10;12(3):e0173737. doi: 10.1371/journal.pone.0173737. eCollection 2017. PubMed
Psychogios MN, Bähr M, Liman J, Knauth M.
One Stop Management in Acute Stroke: First Mothership Patient Transported Directly to the Angiography Suite.
Clin Neuroradiol. 2017 Mar 7. doi: 10.1007/s00062-017-0574-z. [Epub ahead of print] PubMed
Günther R, Balck A, Koch JC, Nientiedt T, Sereda M, Bähr M, Lingor P, Tönges L.
Rho Kinase Inhibition with Fasudil in the SOD1(G93A) Mouse Model of Amyotrophic Lateral Sclerosis-Symptomatic Treatment Potential after Disease Onset.
Front Pharmacol. 2017 Jan 31;8:17. doi: 10.3389/fphar.2017.00017. eCollection 2017. PubMed
Maier IL, Behme D, Schnieder M, Tsogkas I, Schregel K, Kleinknecht A, Wasser K, Bähr M, Knauth M, Psychogios M, Liman J.
Bridging-therapy with intravenous recombinant tissue plasminogen activator improves functional outcome in patients with endovascular treatment in acute stroke.
J Neurol Sci. 2017 Jan 15;372:300-304. doi: 10.1016/j.jns.2016.12.001.PubMed

Publications 2016

Herold S, Kumar P, Jung K, Graf I, Menkhoff H, Schulz X, Bähr M, Hein K.
CatWalk gait analysis in a rat model of multiple sclerosis.
BMC Neurosci. 2016 Nov 30;17(1):78.PubMed
Zhang JN, Michel U, Lenz C, Friedel CC, Köster S, d'Hedouville Z, Tönges L, Urlaub H, Bähr M, Lingor P, Koch JC.
Calpain-mediated cleavage of collapsin response mediator protein-2 drives acute axonal degeneration.
Sci Rep. 2016 Nov 15;6:37050. doi: 10.1038/srep37050.PubMed
Doeppner TR, Doehring M, Kaltwasser B, Majid A, Lin F, Bähr M, Kilic E, Hermann DM.
Ischemic Post-Conditioning Induces Post-Stroke Neuroprotection via Hsp70-Mediated Proteasome Inhibition and Facilitates Neural Progenitor Cell Transplantation.
Mol Neurobiol. 2016 Oct 3. [Epub ahead of print]PubMed
Zerr I, Bähr M.
Is there a role of Tau in Huntington's disease?
J Neurochem. 2016 Oct;139(1):9-10. doi: 10.1111/jnc.13762.PubMed
Obert D, Helms G, Sättler MB, Jung K, Kretzschmar B, Bähr M, Dechent P, Diem R, Hein K.
Brain Metabolite Changes in Patients with Relapsing-Remitting and Secondary Progressive Multiple Sclerosis: A Two-Year Follow-Up Study.
PLoS One. 2016 Sep 16;11(9):e0162583. doi: 10.1371/journal.pone.0162583.PubMed
Maier IL, Karch A, Lipke C, Behme D, Mpotsaris A, Kabbasch C, Liebig T, Faymonville A, Reich A, Nikoubashman O, Buhk JH, von Schoenfeld P, Weber W, Mikolajczyk RT, Bähr M, Knauth M, Kallenberg K, Liman J.
Transluminal angioplasty and stenting versus conservative treatment in patients with symptomatic basilar artery stenosis : Perspective for future clinical trials.
Clin Neuroradiol. 2016 Aug 9. [Epub ahead of print]PubMed
Guerreiro PS, Gerhardt E, Lopes da Fonseca T, Bähr M, Outeiro TF, Eckermann K.
LRRK2 Promotes Tau Accumulation, Aggregation and Release.
Mol Neurobiol. 2016 Jul;53(5):3124-35. doi: 10.1007/s12035-015-9209-z. Epub 2015 May 27.PubMed
Doeppner TR, Kaltwasser B, Sanchez-Mendoza EH, Caglayan AB, Bähr M, Hermann DM.
Lithium-induced neuroprotection in stroke involves increased miR-124 expression, reduced RE1-silencing transcription factor abundance and decreased protein deubiquitination by GSK3β inhibition-independent pathways.
J Cereb Blood Flow Metab. 2016 Apr 28. pii: 0271678X16647738. [Epub ahead of print]PubMed
Doeppner TR, Kaltwasser B, Teli MK, Sanchez-Mendoza EH, Kilic E, Bähr M, Hermann DM.
Conditioned Medium Derived from Neural Progenitor Cells Induces Long-term Post-ischemic Neuroprotection, Sustained Neurological Recovery, Neurogenesis, and Angiogenesis.
Mol Neurobiol. 2016 Feb 9. [Epub ahead of print]PubMed
Dučić T, Carboni E, Lai B, Chen S, Michalke B, Lázaro DF, Outeiro TF, Bähr M, Barski E, Lingor P.
Attenuation of Axonal Degeneration by Calcium Channel Inhibitors Improves Retinal Ganglion Cell Survival and Regeneration After Optic Nerve Crush.
Mol Neurobiol. 2016 Jan 5. [Epub ahead of print]PubMed
Cabral-Calderin Y, Anne Weinrich C, Schmidt-Samoa C, Poland E, Dechent P, Bähr M, Wilke M.
Transcranial alternating current stimulation affects the BOLD signal in a frequency and task-dependent manner.
Hum Brain Mapp. 2016 Jan;37(1):94-121. doi: 10.1002/hbm.23016. Epub 2015 Oct 27.PubMed

Publications 2015

Doeppner TR, Kaltwasser B, Schlechter J, Jaschke J, Kilic E, Bähr M, Hermann DM, Weise J.
Cellular prion protein promotes post-ischemic neuronal survival, angioneurogenesis and enhances neural progenitor cell homing via proteasome inhibition.
Cell Death Dis. 2015 Dec 17;6:e2024. doi: 10.1038/cddis.2015.365.PubMed
Doeppner TR, Pehlke JR, Kaltwasser B, Schlechter J, Kilic E, Bähr M, Hermann DM.
The indirect NMDAR antagonist acamprosate induces postischemic neurologic recovery associated with sustained neuroprotection and neuroregeneration.
J Cereb Blood Flow Metab. 2015 Dec;35(12):2089-97. doi: 10.1038/jcbfm.2015.179. Epub 2015 Jul 29.PubMed
Paschke K, Kagan I, Wüstenberg T, Bähr M, Wilke M.
Trunk rotation affects temporal order judgments with direct saccades: Influence of handedness.
Neuropsychologia. 2015 Dec;79(Pt A):123-37. doi: 10.1016/j.neuropsychologia.2015.10.031. Epub 2015 Oct 27.PubMed
Doeppner TR, Kaltwasser B, Teli MK, Sanchez-Mendoza EH, Kilic E, Bähr M, Hermann DM.
Post-stroke transplantation of adult subventricular zone derived neural progenitor cells--A comprehensive analysis of cell delivery routes and their underlying mechanisms.
Exp Neurol. 2015 Nov;273:45-56. doi: 10.1016/j.expneurol.2015.07.023. Epub 2015 Aug 4.PubMed
Dučić T, Carboni E, Lai B, Chen S, Michalke B, Lázaro DF, Outeiro TF, Bähr M, Barski E, Lingor P.
Alpha-Synuclein Regulates Neuronal Levels of Manganese and Calcium.
ACS Chem Neurosci. 2015 Oct 21;6(10):1769-79. doi: 10.1021/acschemneuro.5b00093. Epub 2015 Aug 25.PubMed
Eckermann K, Kügler S, Bähr M.
Dimerization propensities of Synucleins are not predictive for Synuclein aggregation.
Biochim Biophys Acta. 2015 Aug;1852(8):1658-64. doi: 10.1016/j.bbadis.2015.05.002. Epub 2015 May 8.PubMed
Koch JC, Bitow F, Haack J, d'Hedouville Z, Zhang JN, Tönges L, Michel U, Oliveira LM, Jovin TM, Liman J, Tatenhorst L, Bähr M, Lingor P.
Alpha-Synuclein affects neurite morphology, autophagy, vesicle transport and axonal degeneration in CNS neurons.
Cell Death Dis. 2015 Jul 9;6:e1811. doi: 10.1038/cddis.2015.169.PubMed
Challagundla M, Koch JC, Ribas VT, Michel U, Kügler S, Ostendorf T, Bradke F, Müller HW, Bähr M, Lingor P.
AAV-mediated expression of BAG1 and ROCK2-shRNA promote neuronal survival and axonal sprouting in a rat model of rubrospinal tract injury.
J Neurochem. 2015 Jul;134(2):261-75. doi: 10.1111/jnc.13102. Epub 2015 Apr 13.PubMed
Kumar P, Friebe K, Schallhorn R, Moinfar Z, Nau R, Bähr M, Schütze S, Hein K.
Systemic Escherichia coli infection does not influence clinical symptoms and neurodegeneration in experimental autoimmune encephalomyelitis.
BMC Neurosci. 2015 Jun 19;16:36. doi: 10.1186/s12868-015-0172-4.PubMed
Jaeger HM, Pehlke JR, Kaltwasser B, Kilic E, Bähr M, Hermann DM, Doeppner TR.
The indirect NMDAR inhibitor flupirtine induces sustained post-ischemic recovery, neuroprotection and angioneurogenesis.
Oncotarget. 2015 Jun 10;6(16):14033-44.PubMed
Ribas VT, Schnepf B, Challagundla M, Koch JC, Bähr M, Lingor P.
Early and sustained activation of autophagy in degenerating axons after spinal cord injury.
Brain Pathol. 2015 Mar;25(2):157-70. doi: 10.1111/bpa.12170. Epub 2014 Sep 12.PubMed
Kermer P, Köhn A, Schnieder M, Lingor P, Bähr M, Liman J, Dohm CP.
BAG1 is Neuroprotective in In Vivo and In Vitro Models of Parkinson's Disease.
J Mol Neurosci.2015 Mar;55(3):587-95. doi: 10.1007/s12031-014-0396-2. Epub 2014 Aug 9. PubMed
PubMedBüchner A, Krumova P, Ganesan S, Bähr M, Eckermann K, Weishaupt JH.
Sumoylation of p35 modulates p35/cyclin-dependent kinase (Cdk) 5 complex activity.
Neuromolecular Med. 2015 Mar;17(1):12-23. doi: 10.1007/s12017-014-8336-4. Epub 2014 Nov 13.PubMed
Kumar P, Kretzschmar B, Herold S, Nau R, Kreutzfeldt M, Schütze S, Bähr M, Hein K.
Beneficial effect of chronic Staphylococcus aureus infection in a model of multiple sclerosis is mediated through the secretion of extracellular adherence protein.
J Neuroinflammation. 2015 Feb 3;12:22. doi: 10.1186/s12974-015-0241-8.PubMed
Saal KA, Koch JC, Tatenhorst L, Szegő EM, Ribas VT, Michel U, Bähr M, Tönges L, Lingor P.
AAV.shRNA-mediated downregulation of ROCK2 attenuates degeneration of dopaminergic neurons in toxin-induced models of Parkinson's disease in vitro and in vivo.
Neurobiol Dis. 2015 Jan;73:150-62. doi: 10.1016/j.nbd.2014.09.013. Epub 2014 Oct 2. PubMed
Herold S, Kumar P, Wichert SP, Kretzschmar B, Bähr M, Rossner MJ, Hein K.
Neurodegeneration in Autoimmune Optic Neuritis Is Associated with Altered APP Cleavage in Neurons and Up-Regulation of p53.
PLoS One. 2015 Oct 1;10(10):e0138852. doi: 10.1371/journal.pone.0138852. eCollection 2015.PubMed
Maier IL, Karch A, Mikolajczyk R, Bähr M, Liman J.
Effect of beta-blocker therapy on the risk of infections and death after acute stroke--a historical cohort study.
PLoS One. 2015 Feb 2;10(2):e0116836. doi: 10.1371/journal.pone.0116836. eCollection 2015. Erratum in: PLoS One. 2015;10(3):e0121940. PubMed

Publications 2014

Günther R, Saal KA, Suhr M, Scheer D, Koch JC, Bähr M, Lingor P, Tönges L.
The rho kinase inhibitor Y-27632 improves motor performance in male SOD1(G93A) mice.
Front Neurosci. 2014 Oct 7;8:304. doi: 10.3389/fnins.2014.00304. eCollection 2014. PubMed
Tönges L, Szegö EM, Hause P, Saal KA, Tatenhorst L, Koch JC, D Hedouville Z, Dambeck V, Kügler S, Dohm CP, Bähr M, Lingor P.
Alpha-synuclein mutations impair axonal regeneration in models of Parkinson's disease.
Front Aging Neurosci.2014 Sep 10;6:239. doi: 10.3389/fnagi.2014.00239. eCollection 2014. PubMed
Koch JC, Tönges L, Michel U, Bähr M, Lingor P.
Viral vector-mediated downregulation of RhoA increases survival and axonal regeneration of retinal ganglion cells.
Front Cell Neurosci. 2014 Sep 5;8:273. doi: 10.3389/fncel.2014.00273. eCollection 2014. PubMed
Tatenhorst L, Tönges L, Saal KA, Koch JC, Szegő EM, Bähr M, Lingor P.
Rho kinase inhibition by fasudil in the striatal 6-hydroxydopamine lesion mouse model of Parkinson disease.
J Neuropathol Exp Neurol. 2014 Aug;73(8):770-9. doi: 10.1097/NEN.0000000000000095. PubMed
Ribas VT, Schnepf B, Challagundla M, Koch JC, Bähr M, Lingor P.
Early and sustained activation of autophagy in degenerating axons after spinal cord injury.
Brain Pathol. 2014 Jul 8. doi: 10.1111/bpa.12170. [Epub ahead of print] PubMed
Koch JC, Tönges L, Barski E, Michel U, Bähr M, Lingor P.
ROCK2 is a major regulator of axonal degeneration, neuronal death and axonal regeneration in the CNS.
Cell Death Dis. 2014 May 15;5:e1225. doi: 10.1038/cddis.2014.191. PubMed
Kretzschmar B, Hein K, Moinfar Z, Könnecke B, Sättler MB, Hess H, Weissert R, Bähr M.
Treatment with atacicept enhances neuronal cell death in a rat model of optic neuritis.
J Neuroimmunol. 2014 Mar 15;268(1-2):58-63. doi: 10.1016/j.jneuroim.2014.01.005. Epub 2014 Jan 15. PubMed
Liman J, Deeg S, Voigt A, Voßfeldt H, Dohm CP, Karch A, Weishaupt J, Schulz JB, Bähr M, Kermer P.
CDK5 protects from caspase-induced Ataxin-3 cleavage and neurodegeneration.
J Neurochem. 2014 Feb 18. doi: 10.1111/jnc.12684. [Epub ahead of print] PubMed
Tönges L, Günther R, Suhr M, Jansen J, Balck A, Saal KA, Barski E, Nientied T, Götz AA, Koch JC, Mueller BK, Weishaupt JH, Sereda MW, Hanisch UK, Bähr M, Lingor P.
Rho kinase inhibition modulates microglia activation and improves survival in a model of amyotrophic lateral sclerosis.
Glia. 2014 Feb;62(2):217-32. doi: 10.1002/glia.22601. Epub 2013 Dec 6. PubMed
Tereshchenko J, Maddalena A, Bähr M, Kügler S.
Pharmacologically controlled, discontinuous GDNF gene therapy restores motor function in a rat model of Parkinson's disease.
Neurobiol Dis. 2014 Jan 15;65C:35-42. doi: 10.1016/j.nbd.2014.01.009. [Epub ahead of print] PubMed
Schmitz M, Wulf K, Signore SC, Schulz-Schaeffer WJ, Kermer P, Bähr M, Wouters FS, Zafar S, Zerr I.
Impact of the cellular prion protein on amyloid-β and 3PO-tau processing.
J Alzheimers Dis. 2014;38(3):551-65. doi: 10.3233/JAD-130566. PubMed

Publications 2013

Wasser K, Karch A, Gröschel S, Witzenhausen J, Gröschel K, Bähr M, Liman J.
Plaque morphology detected with Duplex ultrasound before carotid angioplasty and stenting (CAS) is not a predictor of carotid artery in-stent restenosis, a case control study.
BMC Neurol. 2013 Nov 5;13:163 PubMed
Bergner CG, Lang C, Spreer A, Bähr M, Mohr A, Simons M.
Teaching NeuroImages: Ma2 encephalitis presenting as acute panhypopituitarism in a young man.
Neurology. 2013 Nov 5;81(19):e146-7. PubMed
Doeppner TR, Kaltwasser B, Fengyan J, Hermann DM, Bähr M.
TAT-Hsp70 induces neuroprotection against stroke via anti-inflammatory actions providing appropriate cellular microenvironment for transplantation of neural precursor cells.
J Cereb Blood Flow Metab. 2013 Nov;33(11):1778-88. Epub 2013 Jul 24. PubMed
Maddalena A, Tereshchenko J, Bähr M, Kügler S.
Adeno-associated Virus-mediated, Mifepristone-regulated Transgene Expression in the Brain.
Mol Ther Nucleic Acids. 2013 Jul 16;2:e106. PubMed
Dohm CP, Gröschel S, Liman J, Bähr M, Kermer P.
Dropped head sign induced by transdermal application of the dopamine agonist rotigotine in parkinsonian syndrome: a case report.
J Med Case Rep. 2013 Jul 5;7(1):174. PubMed
Sandalon S, Könnecke B, Levkovitch-Verbin H, Simons M, Hein K, Sättler MB, Bähr M, Ofri R.
Functional and structural evaluation of lamotrigine treatment in rat models of acute and chronic ocular hypertension.
Exp Eye Res. 2013 Oct;115:47-56. Epub 2013 Jun 28. PubMed
Doeppner TR, Doehring M, Bretschneider E, Zechariah A, Kaltwasser B, Müller B, Koch JC, Bähr M, Hermann DM, Michel U.
MicroRNA-124 protects against focal cerebral ischemia via mechanisms involving Usp14-dependent REST degradation.
Acta Neuropathol. 2013 Aug;126(2):251-65. Epub 2013 Jun 11. PubMed
Wagner J, Ryazanov S, Leonov A, Levin J, Shi S, Schmidt F, Prix C, Pan-Montojo F, Bertsch U, Mitteregger-Kretzschmar G, Geissen M, Eiden M, Leidel F, Hirschberger T, Deeg AA, Krauth JJ, Zinth W, Tavan P, Pilger J, Zweckstetter M, Frank T, Bähr M, Weishaupt JH, Uhr M, Urlaub H, Teichmann U, Samwer M, Bötzel K, Groschup M, Kretzschmar H, Griesinger C, Giese A.
Anle138b: a novel oligomer modulator for disease-modifying therapy of neurodegenerative diseases such as prion and Parkinson's disease.
Acta Neuropathol. 2013 Jun;125(6):795-813. Epub 2013 Apr 19. PubMed
Taschenberger G, Toloe J, Tereshchenko J, Akerboom J, Wales P, Benz R, Becker S, Outeiro TF, Looger LL, Bähr M, Zweckstetter M, Kügler S.
β-synuclein aggregates and induces neurodegeneration in dopaminergic neurons.
Ann Neurol. 2013 Jul;74(1):109-18. Epub 2013 Aug 6. PubMed
Dučić T, Barski E, Salome M, Koch JC, Bähr M, Lingor P.
X-ray fluorescence analysis of iron and manganese distribution in primary dopaminergic neurons.
J Neurochem. 2013 Jan;124(2):250-61. doi: 10.1111/jnc.12073. Epub 2012 Dec 5. PubMed

Publications 2012

Koch JC, Solis GP, Bodrikov V, Michel U, Haralampieva D, Shypitsyna A, Tönges L, Bähr M, Lingor P, Stuermer CA.
Upregulation of reggie-1/flotillin-2 promotes axon regeneration in the rat optic nerve in vivo and neurite growth in vitro.
Neurobiol Dis. 2012 Nov 19. doi:pii: S0969-9961(12)00370-1. 10.1016/j.nbd.2012.11.007. PubMed
Doeppner TR, Mlynarczuk-Bialy I, Kuckelkorn U, Kaltwasser B, Herz J, Hasan MR, Hermann DM, Bähr M.
The novel proteasome inhibitor BSc2118 protects against cerebral ischaemia through HIF1A accumulation and enhanced angioneurogenesis.
Brain. 2012 Nov;135(Pt 11):3282-97. PubMed
Tönges L, Frank T, Tatenhorst L, Saal KA, Koch JC, Szego ÉM, Bähr M, Weishaupt JH, Lingor P.
Inhibition of rho kinase enhances survival of dopaminergic neurons and attenuates axonal loss in a mouse model of Parkinson's disease.
Brain. 2012 Nov;135(Pt 11):3355-70. Epub 2012 Oct 19. PubMed
Sühs KW, Hein K, Sättler MB, Görlitz A, Ciupka C, Scholz K, Käsmann-Kellner B, Papanagiotou P, Schäffler N, Cordula Restemeyer C, Bittersohl D, Hassenstein A, Seitz B, Reith W, Fassbender K, Hilgers R, Heesen C, Bähr M, Diem R.
A randomized, double-blind, phase II study on erythropoietin in optic neuritis.
Ann Neurol 2012 Aug;72(2):199-210. PubMed
Müller HW, Sendtner M, Bähr M.
Molecular basis of neural repair mechanisms.
Cell Tissue Res. 2012 Jul;349(1):1-4. PubMed
Lange K, Bähr M, Hein K.
Author response: Retinal nerve fiber layer thickness measurements in rats with the spectral domain optical coherence tomography.
Invest Ophthalmol Vis Sci. 2012 Jun 8;53(7):3570-1. Print 2012 Jun. No abstract available. PubMed
Doeppner TR, Ewert TA, Tönges L, Herz J, Zechariah A, ElAli A, Ludwig AK, Giebel B, Nagel F, Dietz GP, Weise J, Hermann DM, Bähr M.
Transduction of neural precursor cells with TAT-heat shock protein 70 chaperone: therapeutic potential against ischemic stroke after intrastriatal and systemic transplantation.
Stem Cells. 2012 Jun;30(6):1297-310. doi: 10.1002/stem.1098. PubMed
Koziolek MJ, Tampe D, Bähr M, Dihazi H, Jung K, Fitzner D, Klingel R, Müller GA, Kitze B.
Immunoadsorption therapy in patients with multiple sclerosis with steroid-refractory optical neuritis.
J Neuroinflammation. 2012 Apr 26;9:80. PubMed
Bahari-Javan S, Maddalena A, Kerimoglu C, Wittnam J, Held T, Bähr M, Burkhardt S, Delalle I, Kügler S, Fischer A, Sananbenesi F.
HDAC1 Regulates Fear Extinction in Mice.
J Neurosci. 2012 Apr 11;32(15):5062-5073. PubMed
Günther R, Suhr M, Koch JC, Bähr M, Lingor P, Tönges L.
Clinical Testing and Spinal Cord Removal in a Mouse Model for Amyotrophic Lateral Sclerosis (ALS).
J Vis Exp. 2012 Mar 17;(61). PubMed
Frank T, Klinker F, Falkenburger BH, Laage R, Lühder F, Göricke B, Schneider A, Neurath H, Desel H, Liebetanz D, Bähr M, Weishaupt JH.
Pegylated granulocyte colony-stimulating factor conveys long-term neuroprotection and improves functional outcome in a model of Parkinson's disease.
Brain. 2012 Mar 16. [Epub ahead of print] PubMed
Weishaupt JH, Ganser C, Bähr M.
Inflammatory demyelinating CNS disorder in a case of X-linked Charcot-Marie-Tooth disease: positive response to natalizumab.
J Neurol. 2012 Mar 13. [Epub ahead of print] PubMed
Lingor P, Koch JC, Tönges L, Bähr M.
Axonal degeneration as a therapeutic target in the CNS.
Cell Tissue Res. 2012 Mar 6. [Epub ahead of print] PubMed
Taschenberger G, Garrido M, Tereshchenko Y, Bähr M, Zweckstetter M, Kügler S.
Aggregation of αSynuclein promotes progressive in vivo neurotoxicity in adult rat dopaminergic neurons.
Acta Neuropathol. 2012 May;123(5):671-83. Epub 2011 Dec 14. PubMed
Hein K, Gadjanski I, Kretzschmar B, Lange K, Diem R, Sättler MB, Bähr M.
An optical coherence tomography study on degeneration of retinal nerve fiber layer in rats with autoimmune optic neuritis.
Invest Ophthalmol Vis Sci. 2012 Jan 20;53(1):157-63. Print 2012 Jan. PubMed
Drinkut A, Tereshchenko Y, Schulz JB, Bähr M, Kügler S.
Efficient gene therapy for Parkinson's disease using astrocytes as hosts for localized neurotrophic factor delivery.
Mol Ther. 2012 Mar;20(3):534-43. Epub 2011 Nov 15. PubMed
Liman J, Wellmer A, Rostasy K, Bähr M, Kermer P.
Transcranial ultrasound in neurodegeneration with brain iron accumulation (NBIA).
Eur J Paediatr Neurol. 2012 Mar;16(2):175-8. Epub 2011 Aug 3.
PubMed

Publications 2011

Tönges L, Koch JC, Bähr M, Lingor P.
ROCKing Regeneration: Rho Kinase Inhibition as Molecular Target for Neurorestoration.
Front Mol Neurosci. 2011;4:39. Epub 2011 Nov 3. PubMed
Koch JC, Knöferle J, Tönges L, Michel U, Bähr M, Lingor P.
Imaging of rat optic nerve axons in vivo.
Nat Protoc. 2011 Nov 3;6(12):1887-96. PubMed
Koch JC, Barski E, Lingor P, Bähr M, Michel U.
Plasmids containing NRSE/RE1 sites enhance neurite outgrowth of retinal ganglion cells via sequestration of REST independent of NRSE dsRNA expression.
FEBS J 2011 Sep;278(18):3472-83. PubMed
Doeppner TR, Bretschneider E, Doehring M, Segura I, Sentürk A, Acker-Palmer A, Hasan MR, Elali A, Hermann DM, Bähr M.
Enhancement of endogenous neurogenesis in ephrin-B3 deficient mice after transient focal cerebral ischemia.
Acta Neuropathol 2011 Jul 21. [Epub ahead of print] PubMed
Krumova P, Meulmeester E, Garrido M, Tirard M, Hsiao HH, Bossis G, Urlaub H, Zweckstetter M, Kügler S, Melchior F, Bähr M, Weishaupt JH.
Sumoylation inhibits alpha-synuclein aggregation and toxicity.
J Cell Biol 2011 Jul 11;194(1):49-60. PubMed
Liman J, von Gottberg P, Bähr M, Kermer P.
Femoral nerve palsy caused by ileopectineal bursitis after total hip replacement: a case report.
J Med Case Reports 2011 May 18;5(1):190. PubMed
Gadjanski I, Williams SK, Hein K, Sättler MB, Bähr M, Diem R.
Correlation of optical coherence tomography with clinical and histopathological findings in experimental autoimmune uveoretinitis.
Exp Eye Res 2011 Jul;93(1):82-90. Epub 2011 May 11. PubMed
Tönges L, Planchamp V, Koch JC, Herdegen T, Bähr M, Lingor P.
JNK Isoforms Differentially Regulate Neurite Growth and Regeneration in Dopaminergic Neurons In Vitro.
J Mol Neurosci 2011 Apr 6. [Epub ahead of print] PubMed
Tönges L, Ostendorf T, Lamballe F, Genestine M, Dono R, Koch JC, Bähr M, Maina F, Lingor P.
Hepatocyte growth factor protects retinal ganglion cells by increasing neuronal survival and axonal regeneration in vitro and in vivo.
J Neurochem 2011 Jun;117(5):892-903. Epub 2011 Apr 26. PubMed
Schmidt H, Schramm P, Fuchs T, Bähr M, Lingor P.
[Arndt-Gottron syndrome with encephalopathy : Complete recovery after immunosuppressive therapy.].
Nervenarzt 2011 Mar 10. [Epub ahead of print] German PubMed
Rau CR, Hein K, Sättler MB, Kretzschmar B, Hillgruber C, McRae BL, Diem R, Bähr M.
Anti-inflammatory effects of FTY720 do not prevent neuronal cell loss in a rat model of optic neuritis.
Am J Pathol 2011 Apr;178(4):1770-81. Epub 2011 PubMed
Garrido M, Tereshchenko Y, Zhevtsova Z, Taschenberger G, Bähr M, Kügler S.
Glutathione depletion and overproduction both initiate degeneration of nigral dopaminergic neurons.
Acta Neuropathol 2011 Apr;121(4):475-85. Epub 2010 Dec 30. PubMed
Doeppner TR, Kaltwasser B, ElAli A, Zechariah A, Hermann DM, Bähr M.
Acute hepatocyte growth factor treatment induces long-term neuroprotection and stroke recovery via mechanisms involving neural precursor cell proliferation and differentiation.
J Cereb Blood Flow Metab 2011 May;31(5):1251-62. Epub 2010 Dec PubMed

Publications 2010

Göricke B, Lingor P, Stadelmann-Nessler C, Bähr M, Kastrup A, Kermer P.
Cerebellar-type multiple system atrophy presenting with leucoencephalopathy.
J Neurol Neurosurg Psychiatry 2010 Nov 28. [Epub ahead of print] PubMed
Bähr M.
Special Issue on Multiple Sclerosis.
Exp Neurol 2010 Jun 23. PubMed
Doeppner TR, El Aanbouri M, Dietz GP, Weise J, Schwarting S, Bähr M.
Transplantation of TAT-Bcl-x(L)-transduced neural precursor cells: Long-term neuroprotection after stroke.
Neurobiol Dis 2010 Jun 8. PubMed
Shevtsova Z, Garrido M, Weishaupt J, Saftig P, Bähr M, Lühder F, Kügler S.
CNS-expressed cathepsin D prevents lymphopenia in a murine model of congenital neuronal ceroid lipofuscinosis.
Am J Pathol 2010 Jul;177(1):271-9. Epub 2010 May 20. PubMed
Gade K, Bähr M, Kermer P.
Recurrent episodes of stroke-like symptoms due to accidental intoxication with doxepin.
J Neuropsychiatry Clin Neurosci 2010 Spring;22(2):E23. PubMed
Koch JC, Knöferle J, Tönges L, Ostendorf T, Bähr M, Lingor P.
Acute axonal degeneration in vivo is attenuated by inhibition of autophagy in a calcium-dependent manner.
Autophagy 2010 Jul 22;6(5). [Epub ahead of print] PubMed
Knöferle J, Koch JC, Ostendorf T, Michel U, Planchamp V, Vutova P, Tönges L, Stadelmann C, Brück W, Bähr M, Lingor P.
Mechanisms of acute axonal degeneration in the optic nerve in vivo.
Proc Natl Acad Sci U S A 2010 Mar 30;107(13):6064-9. Epub 2010 Mar 15. PubMed
Knöferle J, Ramljak S, Koch JC, Tönges L, Asif AR, Michel U, Wouters FS, Heermann S, Krieglstein K, Zerr I, Bähr M, Lingor P.
TGF-beta 1 enhances neurite outgrowth via regulation of proteasome function and EFABP.
Neurobiol Dis 2010 Jun;38(3):395-404. Epub 2010 Mar 6. PubMed
Deeg S, Gralle M, Sroka K, Bähr M, Wouters FS, Kermer P.
BAG1 restores formation of functional DJ-1 L166P dimers and DJ-1 chaperone activity.
J Cell Biol 2010 Feb 22;188(4):505-13. Epub 2010 Feb 15. PubMed
Doeppner TR, Dietz GP, Weise J, Bähr M.
Protection of hippocampal neurogenesis by TAT-Bcl-x(L) after cerebral ischemia in mice.
Exp Neurol 2010 Jun;223(2):548-56. Epub 2010 Feb 12. PubMed

Publications 2009

Ehrenreich H, Weissenborn K, Prange H, Schneider D, Weimar C, Wartenberg K, Schellinger PD, Bohn M, Becker H, Wegrzyn M, Jähnig P, Herrmann M, Knauth M, Bähr M, Heide W, Wagner A, Schwab S, Reichmann H, Schwendemann G, Dengler R, Kastrup A, Bartels C; EPO Stroke Trial Group.
Recombinant human erythropoietin in the treatment of acute ischemic stroke.
Stroke 2009 Dec;40(12):e647-56. Epub 2009 Oct 15. PubMed
Bermel C, Tönges L, Planchamp V, Gillardon F, Weishaupt JH, Dietz GP, Bähr M, Lingor P.
Combined inhibition of Cdk5 and ROCK additively increase cell survival, but not the regenerative response in regenerating retinal ganglion cells.
Mol Cell Neurosci 2009 Dec;42(4):427-37. Epub 2009 Sep 25. PubMed
Sättler MB, Bähr M.
Future neuroprotective strategies.
Exp Neurol 2009 Aug 27. PubMed
Sroka K, Voigt A, Deeg S, Reed JC, Schulz JB, Bähr M, Kermer P.
BAG1 modulates huntingtin toxicity, aggregation, degradation, and subcellular distribution.
J Neurochem 2009 Nov;111(3):801-7. Epub 2009 Aug 27. PubMed
Gadjanski I, Boretius S, Williams SK, Lingor P, Knöferle J, Sättler MB, Fairless R, Hochmeister S, Sühs KW, Michaelis T, Frahm J, Storch MK, Bähr M, Diem R.
Role of n-type voltage-dependent calcium channels in autoimmune optic neuritis.
Ann Neurol 2009 Jul;66(1):81-93. PubMed
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Tauber SC, Ebert S, Weishaupt JH, Reich A, Nau R, Gerber J.
Stimulation of Toll-Like Receptor 9 by Chronic Intraventricular Unmethylated Cytosine-Guanine DNA Infusion Causes Neuroinflammation and Impaired Spatial Memory
J Neuropathol Exp Neurol October 2009 - Volume 68 - Issue 10 - pp 1116-1124. No Link
Bermel C, Tönges L, Planchamp V, Gillardon F, Weishaupt JH, Dietz GP, Bähr M, Lingor P.
Combined inhibition of Cdk5 and ROCK additively increase cell survival, but not the regenerative response in regenerating retinal ganglion cells.
Mol Cell Neurosci. 2009 Sep 25. [Epub ahead of print] PubMed
Zschüntzsch J, Dibaj P, Pilgram S, Kötting J, Gerding WM, Neusch C.
Severe demyelinating hypertrophic polyneuropathy caused by a de novo frameshift mutation within the intracellular domain of myelin protein zero (MPZ/P0)
J Neurol Sci PubMed
Frank T, Schlachetzki JCM, Goricke B, Meuer K, Rohde G, Dietz GPH, Bahr M, Schneider A, Weishaupt JH.
Both systemic and local application of Granulocyte-colony stimulating factor (G-CSF) is neuroprotective after retinal ganglion cell axotomy
BMC Neuroscience 2009, 10:49. PubMed
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Nagel F, Bähr M, Dietz GP.
Tyrosine hydroxylase-positive amacrine interneurons in the mouse retina are resistant against the application of various Parkinsonian toxins.
Brain Res Bull. 2009 Apr 27. PubMed
Doeppner TR, Nagel F, Dietz GP, Weise J, Tönges L, Schwarting S, Bähr M.
TAT-Hsp70-mediated neuroprotection and increased survival of neuronal precursor cells after focal cerebral ischemia in mice.
J Cereb Blood Flow Metab. 2009 Apr 22. PubMed
Dohm CP, Pilgram SM, Liman J, Bähr M, Mohr A, Kermer P.
[Differential diagnosis of Parkinson's syndromes--an overview].
Dtsch Med Wochenschr. 2009 Apr;134(17):892-6. Epub 2009 Apr 15. Review. PubMed
Ebert S, Pilgram SM, Bähr M, Kermer P.
Bilateral ophthalmoplegia due to symmetric cavernous sinus metastasis from gastric adenocarcinoma.
J Neurol Sci. 2009 Apr 15;279(1-2):106-8. PubMed
Doeppner TR, Dietz GP, El Aanbouri M, Gerber J, Witte OW, Bähr M, Weise J.
TAT-Bcl-x(L) improves survival of neuronal precursor cells in the lesioned striatum after focal cerebral ischemia.
Neurobiol Dis. 2009 Apr;34(1):87-94. PubMed

Publications 2008

Rohde G, Kermer P, Reed JC, Bähr M, Weishaupt JH.
Neuron-specific overexpression of the co-chaperone Bcl-2-associated athanogene-1 in superoxide dismutase 1(G93A)-transgenic mice.
Neuroscience. 2008 Dec 10;157(4):844-9. Epub 2008 Oct 4. PubMed
Sättler MB, Williams SK, Neusch C, Otto M, Pehlke JR, Bähr M, Diem R.
Flupirtine as Neuroprotective Add-On Therapy in Autoimmune Optic Neuritis.
Am J Pathol. 2008 131(Pt 10):2606-19. PubMed
Planchamp V, Bermel CM, Tönges L, Ostendorf T, Kügler S, Reed JC, Kermer P, Bähr M, Lingor P.
BAG1 promotes axonal outgrowth and regeneration in vivo via Raf-1 and reduction of ROCK activity.
Brain. 2008 131(Pt 10):2606-19. PubMed
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Schmidt J, Barthel K, Wrede A, Salajegheh M, Bähr M, Dalakas MC.
Interrelation of inflammation and APP in sIBM: IL-1 beta induces accumulation of beta-amyloid in skeletal muscle.
Brain. 2008 May;131(Pt 5):1228-40. Epub 2008 Apr 17. PubMed
Schwarting S, Litwak S, Hao W, Bähr M, Weise J, Neumann H.
Hematopoietic Stem Cells Reduce Postischemic Inflammation and Ameliorate Ischemic Brain Injury.
Stroke. 2008 Oct;39(10):2867-75. Epub 2008 Jul 24. PubMed
Heller T, Nagel I, Ehrlich B, Bähr M, Strik H.
Automated cerebrospinal fluid cytology.
Anal Quant Cytol Histol. 2008 Jun;30(3):139-44. PubMed
Diem R, Demmer I, Boretius S, Merkler D, Schmelting B, Williams SK, Sättler MB, Bähr M, Michaelis T, Frahm J, Brück W, Fuchs E.
Autoimmune optic neuritis in the common marmoset monkey: comparison of visual evoked potentials with MRI and histopathology.
Invest Ophthalmol Vis Sci. 2008 Aug;49(8):3707-14. Epub 2008 Apr 30. PubMed
Weise J, Doeppner TR, Müller T, Wrede A, Schulz-Schaeffer W, Zerr I, Witte OW, Bähr M.
Overexpression of cellular prion protein alters postischemic Erk1/2 phosphorylation but not Akt phosphorylation and protects against focal cerebral ischemia.
Restor Neurol Neurosci. 2008;26(1):57-64. PubMed
Liman J, Faida L, Dohm CP, Reed JC, Bähr M, Kermer P.
Subcellular distribution affects BAG1 function.
Brain Res. 2008 Mar 10;1198:21-6. Epub 2008 Jan 16. PubMed
Dohm CP, Kermer P, Bähr M.
Aggregopathy in Neurodegenerative Diseases: Mechanisms and Therapeutic Implication.
Neurodegener Dis. 2008 Feb 29. PubMed
Dietz GP, Bähr M.
Synthesis of cell-penetrating peptides and their application in neurobiology.
Methods Mol Biol. 2007;399:181-98. Review. PubMed
Hein Née Maier K, Köhler A, Diem R, Sättler MB, Demmer I, Lange P, Bähr M, Otto M.
Biological markers for axonal degeneration in CSF and blood of patients with the first event indicative for multiple sclerosis.
Neurosci Lett. 2008 May 2;436(1):72-6. Epub 2008 Mar 5. PubMed
Nagel F, Dohm CP, Bähr M, Wouters FS, Dietz GPH.
Quantitative evaluation of chaperone activity and neuroprotection by different preparations of a cell-penetrating Hsp70.
J Neurosci Meth. 2008 30;171(2):226-32. PubMed
Boretius S, Gadjanski I, Demmer I, Bähr M, Diem R, Michaelis T, Frahm J.
MRI of optic neuritis in a rat model.
Neuroimage. 2008 41(2):323-34. PubMed

Publications 2007

Shi H, Patschan D, Dietz GP, Bahr M, Plotkin M, Goligorsky MS.
Glial cell line-derived neurotrophic growth factor increases motility and survival of cultured mesenchymal stem cells and ameliorates acute kidney injury.
Am J Physiol Renal Physiol. 2007 Nov 14; [Epub ahead of print]. PubMed
Nagel F, Falkenburger B, Tönges L, Kowsky S, Pöppelmeyer C, Schulz JB, Bähr M, Dietz GPH.
Tat-Hsp70 protects dopaminergic neurons in midbrain cultures and in the substantia nigra in models of Parkinson’s disease.
J Neurochem. 2008 May;105(3):853-64. Epub 2007 Dec 24. PubMed
Dietz GP, Stockhausen Née Peters KV, Dietz B, Falkenburger BH, Valbuena P, Opazo F, Lingor P, Meuer K, Weishaupt JH, Schulz JB, Bähr M.
Membrane-permeable Bcl-xL prevents MPTP-induced dopaminergic neuronal loss in the substantia nigra.
J Neurochem. 2008 104(3):757-65. PubMed
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Koeberle PD, Bähr M.
The Upregulation of GLAST-1 is an indirect anti-apoptotic mechanism of GDNF and Neurturin in the adult CNS.
Cell Death Differ. 2008 Mar;15(3):471-83. Epub 2007 Dec 7. PubMed
Loh SH, Francescut L, Lingor P, Bähr M, Nicotera P.
Identification of new kinase clusters required for neurite outgrowth and retraction by a loss-of-function RNA interference screen.
Cell Death Differ. 2008 15(2):283-98. PubMed
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Lingor P*, Tönges L*, Pieper N, Bermel C, Barski E, Planchamp V, Bähr M.
ROCK inhibition and CNTF interact on intrinsic signalling pathways and differentially regulate survival and regeneration in retinal ganglion cells
Brain. 2008 Jan;131(Pt 1):250-63. Epub 2007 Dec 5. * equal contribution. PubMed
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Sättler MB, Togni M, Gadjanski I, Sühs KW, Meyer N, Bähr M, Diem R.
Strain-specific susceptibility for neurodegeneration in a rat model of autoimmune optic neuritis.
J Neuroimmunol. Jan;193(1-2):77-86. Epub 2007 Nov 26. PubMed
Dietz GP, Dietz B, Bähr M.
Bcl-x(L) protects cerebellar granule neurons against the late phase, but not against the early phase of glutamate-induced cell death.
Brain Res. 2007 Aug 20;1164:136-41. Epub 2007 Jun 21. PubMed
Ganesan S, Rohde G, Eckermann K, Sroka K, Schaefer MKE, Dohm CP, Kermer P, Haase G, Wouters FS, Bähr M, Weishaupt JH.
Mutant SOD1 detoxification mechanisms in intact single cells
Cell Death Differ. 2007 Nov 9; [Epub ahead of print]. PubMed
Lingor P, Bähr M.
Targeting neurological disease with RNAi.
Mol. BioSyst. 2007 Nov;3(11):773-80. Epub 2007 Aug 29. PubMed
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Engelhorn T, Hufnagel A, Weise J, Bähr M, Dörfler A.
Monitoring of acute generalized status epilepticus using multilocal diffusion MR imaging: early prediction of regional neuronal damage.
Am J Neuroradiol. 2007 Feb;28(2):321-7. PubMed
Peroni D, Negro A, Bähr M, Dietz GPH.
Intracellular delivery of Neuroglobin using HIV-1 TAT protein transduction domain fails to protect against oxygen and glucose deprivation.
Neurosci Lett. 2007 Jun 27;421(2):110-4. Epub 2007 Jun 2. PubMed
Esposito A, Dohm CP, Bähr M, Wouters FS.
Unsupervised Fluorescence Lifetime Imaging Microscopy for High-Content and High-Throughput Screening.
Molecular and Cellular Proteomics. 2007 Aug;6(8):1446-54. Epub 2007 May 16. PubMed
Crome O, Doeppner TR, Schwarting S, Müller B, Bähr M, Weise J.
Enhanced poly(ADP-ribose) polymerase-1 activation contributes to recombinant tissue plasminogen activator-induced aggravation of ischemic brain injury in vivo.
J Neurosci Res. 2007 85(8): 1734-43 PubMed
Esposito A, Dohm CP, Kermer P, Bähr M, Wouters FS.
Alpha-Synuclein and its disease-related mutants interact differentially with the microtubule protein tau and associate with the actin cytoskeleton.
Neurobiol. Dis. 2007 26(3):521-31. PubMed
Lingor P, Teusch N, Schwarz K, Mueller R, Mack H, Bähr M and Mueller BK.
Inhibition of Rho kinase (ROCK) increases neurite outgrowth on CSPG in vitro and axonal regeneration in the adult optic nerve in vivo.
J Neurochem. 2007 Oct;103(1):181-9. Epub 2007 Jul 2. PubMed
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Strik HM, Schmidt K, Lingor P, Tönges L, Kugler W, Nitsche M, Rabinovich G, Bähr M.
Galectin-1 expression in human glioma cells: modulation by ionizing radiation and effects on tumor cell proliferation and migration.
Oncol Rep. 2007 Aug;18(2):483-8. PubMed
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Neusch C, Senderek J, Eggermann T, Elolf E, Bähr M and Schneider-Gold C.
Mitofusin 2 gene mutation (R94Q) causing severe early-onset axonal polyneuropathy (CMT2a).
Eur J Neurol. 2007 14(5):575-7. PubMed
Liebetanz D, Baier PC, Paulus W, Meuer K, Bähr M, Weishaupt JH.
A highly sensitive automated complex running wheel test to detect latent motor deficits in the mouse MPTP model of Parkinson's disease.
Exp Neurol. 2007; 205(1):207-13. PubMed
Tönges L, Schlachetzki JCM, Weishaupt JH, Bähr M.
Hematopoietic Cytokines – on the Verge of Conquering Neurology
Current Molecular Medicine 2007 Mar;7(2):157-170 PubMed
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Meuer K, Suppanz IE, Lingor P, Planchamp V, Goricke B, Fichtner L, Braus GH, Dietz GP, Jakobs S, Bahr M, Weishaupt JH.
Cyclin-dependent kinase 5 is an upstream regulator of mitochondrial fission during neuronal apoptosis.
Cell Death Differ. 2007 Jan 12; 14(4):651-61. PubMed
Diem R, Sattler MB, Bahr M.
Neurodegeneration and -protection in autoimmune CNS inflammation.
J Neuroimmunol. 2006 Dec 22; [Epub ahead of print] PubMed
Maier K, Merkler D, Gerber J, Taheri N, Kuhnert AV, Williams SK, Neusch C, Bähr M, Diem R.
Multiple neuroprotective mechanisms of minocycline in autoimmune CNS inflammation
Neurobiol Dis. accepted. 2007 Mar;25(3):514-25. Epub 2007 Jan 18. PubMed

Publications 2006

Bahr M, Lingor P.
Brain repair: Experimental treatment strategies, neuroprotective and repair strategies in the lesioned adult CNS.
Adv Exp Med Biol. 2006;557:148-63. PubMed
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Kaiser M, Maletzki I, Hulsmann S, Holtmann B, Schulz-Schaeffer W, Kirchhoff F, Bahr M, Neusch C.
Progressive loss of a glial potassium channel (KCNJ10) in the spinal cord of the SOD1 (G93A) transgenic mouse model of amyotrophic lateral sclerosis.
J Neurochem. 2006 Aug 21; [Epub ahead of print] PubMed
Nitzan A, Kermer P, Shirvan A, Bahr M, Barzilai A, Solomon AS.
Examination of cellular and molecular events associated with optic nerve axotomy.
Glia. 2006 Nov 1;54(6):545-56. PubMed
Shevtsova Z, Malik I, Garrido M, Scholl U, Bahr M, Kugler S.
Potentiation of in vivo neuroprotection by BclX(L) and GDNF co-expression depends on post-lesion time in deafferentiated CNS neurons.
Gene Ther. 2006 Jul 13; [Epub ahead of print] PubMed
Maier K, Kuhnert AV, Taheri N, Sättler MB, Storch MK, Williams SK, Bähr M, Diem R.
Effects of glatiramer acetate and interferon-beta on neurodegeneration in a model of multiple sclerosis: a comparative study.
Am J Pathol. 2006 Oct;169(4):1353-64 PubMed
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Pietrancosta N, Moumen A, Dono R, Lingor P, Planchamp V, Lamballe F, Bahr M, Kraus JL, Maina F.
Imino-tetrahydro-benzothiazole Derivatives as p53 Inhibitors: Discovery of a Highly Potent in Vivo Inhibitor and Its Action Mechanism.
J Med Chem. 2006 Jun 15;49(12):3645-3652. PubMed
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Sättler MB, Demmer I, Williams SK, Maier K, Merkler D, Gadjanski I, Stadelmann C, Bähr M, Diem R.
Effects of interferon-beta-1a on neuronal survival under autoimmune inflammatory conditions.
Exp Neurol. 2006 Jun 7; [Epub ahead of print] PubMed
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Tönges L, Lingor P, Egle R, Dietz GPH, Fahr A, Bähr M.
tearylated octaarginine and artificial virus-like particles for transfection of siRNA into primary rat neurons.
RNA. 2006 Jul;12(7):1431-8. Epub 2006 May 12. PubMed
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Dohm CP, Siedenberg S, Liman J, Esposito A, Wouters FS, Reed JC, Bähr M, Kermer P
Bax inhibitor-1 protects neurons from oxygen-glucose deprivation.
J Mol Neurosci. 2006;29(1):1-8. PubMed
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Hotchkiss RS, McConnell KW, Kelley K, Davis G, Chang KC, Schwulst S, Dunne JC, Dietz GPH, Bähr M, McDunn JE, Karl IE, Coopersmith C, Piwnica-Worms D.
Protection against sepsis-induced lymphocyte apoptosis via in vivo delivery of TAT fusion compounds.
J Immunol. 2006 May 1;176(9):5471-7. PubMed
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Dietz GPH, Dietz B, Bähr M.
Bcl-xL increases axonal numbers but not axonal elongation from rat retinal explants.
Brain Res Bull 2006 Jun 30;70(2):117-23. Epub 2006 May 2. PubMed
Weise J, Sandau R, Schwarting S, Crome O, Wrede A, Schulz-Schaeffer W, Zerr I, Bähr M.
Deletion of Cellular Prion Protein Results in Reduced Akt Activation, Enhanced Postischemic Caspase-3 Activation, and Exacerbation of Ischemic Brain Injury.
Stroke. 2006 Mar 30; [Epub ahead of print]. PubMed
Meuer K, Pitzer C, Teismann P, Krüger C, Göricke B, Laage R, Lingor P, Peters K, Schlachetzki JCM, Kobayashi K, Dietz GPH, Weber D, Ferger B, Schäbitz WR, Bach A, Schulz JB, Bähr M, Schneider A, Weishaupt JH.
Granulocyte-colony stimulating factor (G-CSF) is neuroprotective in a model of Parkinson's disease.
J Neurochem 2006 Mar 29; [Epub ahead of print]. PubMed
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Dietz GPH, Valbuena PC, Dietz B, Meuer K, Müller P, Weishaupt JH, Bähr M.
Application of a blood-brain barrier-penetrating form of GDNF in a mouse model for Parkinson's Disease.
rain Res 2006 1082:61-66. PubMed
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Malik I, Garrido M, Bähr M, Kügler S, Michel U.
Comparison of test systems for RNAinterference.
Biochem Biophys Res Commun. 2006 Mar 3;341(1):245-53. PubMed
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Publications 2005

Guégan C, Braudeau J, Couriaud C, Dietz GPH, Bähr M, Onténiente B.
PTD-XIAP fusion proteins protect against cerebral ischemia by anti-apoptotic and transcriptional regulatory mechanisms.
Neurobiol Dis 2006 Apr;22(1):177-86. Epub 2005 Dec 19. PubMed
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Kermer P, Wellmer A, Crome O, Mohr A, Knauth M, Bähr M.
Transcranial color-coded duplex sonography in suspected acute basilar artery occlusion.
Ultrasound Med Biol 2006 Mar;32(3):315-20. PubMed
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